产品描述:
AC-55541 is a proteinase-activated receptor 2 (PAR2) agonist that displays no activity at other PAR subtypes or at over 30 other receptors involved in nociception and inflammation.{30968} It stimulates cell proliferation, phosphatidylinositol hydrolysis, and calcium mobilization in in vitro functional assays (pEC50s = 6.7, 5.9, and 6.6, respectively).{30968} Intrapaw administration of 3-10 mg/kg AC-55541 elicited pronociceptive activity in vivo.{30968}