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α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
品牌： Cayman
产品货号： 29923-10 mg
规格： 10 mg

报价：
折后价：

数量： - +
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  • 产品名称:
    α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
  • 别名:
    Ac-SYSMEHFRWGKPV-NH2|α-Melanocyte-stimulating Hormone
  • 产品描述:
    α-Melanocyte-stimulating hormone (α-MSH) is a 13-amino acid peptide hormone produced by post-translational processing of proopiomelanocortin (POMC) in the pituitary gland, as well as in keratinocytes, astrocytes, monocytes, and gastrointestinal cells.{47500} It is an agonist of melanocortin receptor 3 (MC3R) and MC4R that induces cAMP production in Hepa cells expressing the human receptors (EC50s = 0.16 and 56 nM, respectively).{45139} α-MSH (100 pM) reduces S. aureus colony formation and C. albicans germ tube formation in vitro.{55058} It inhibits endotoxin-, ceramide-, TNF-α-, or okadaic acid-induced activation of NF-κB in U937 cells.{47500} α-MSH reduces IL-6- or TNF-α-induced ear edema in mice.{55059} It also prevents the development of adjuvant-induced arthritis in rats and increases survival in a mouse model of septic shock. Increased plasma levels of α-MSH are positively correlated with delayed disease progression and reduced death in patients with HIV.{47500}
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  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    1664.9
  • 产品形式:
    A solid
  • 存储溶液:
  • 有效期:
    1460
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  • 纯度:
    ≥98%
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  • CAS号:
    171869-93-5
  • 分子式:
    C77H109N21O19S • XCF3COOH
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