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Pam3CSK4 (trifluoroacetate salt)
品牌: Cayman
产品货号: 24126
规格: 1 mg

报价:
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数量: - +
产品详情
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  • 产品名称:
    Pam3CSK4 (trifluoroacetate salt)
  • 别名:
    Pam3Cys-Ser-(Lys)4
  • 产品描述:
    Pam3CSK4 is a synthetic bacterial lipopeptide that binds to and acts as an agonist at toll-like receptor 2 (TLR2).{38691} It induces proliferation of isolated mouse spleen cells and activates lymphocytes at a concentration of 50 µg/ml.{38692} Pam3CSK4 is a potent immune adjuvant in mice, enhancing the response to antigen, as measured by IgM and IgG levels, when used at a dose of 200 µg/animal. It inhibits Th1 and Th2 responses, suppresses eosinophil infiltration, and induces CD4+ T cell apoptosis in a mouse model of allergic conjunctivitis.{38693} Pam3CSK4 (50 µg) decreases lesion size and parasite burden in genetically-resistant and -susceptible mice when administered with L. major to induce leishmaniasis.{38694} It also enhances Th1 responses and stimulates IL-17 production in the early phase of infection.
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  • 阳性对照:
  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    1510.2
  • 产品形式:
    A lyophilized powder
  • 存储溶液:
  • 有效期:
    1460
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  • 纯度:
    ≥95%
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  • 分子式:
    C81H156N10O13S • XCF3COOH
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