产品描述:
BRL 37344 is a selective agonist of β3-adrenergic receptors with Ki values of 0.43, 9.17, and 37.9 µM for β3, β2, and β1, respectively.{25395} β3-Adrenoceptors are expressed in adipose tissue as well as endothelial and myocardial tissues.{30103} This compound has been used to explore the role of these receptors in the regulation of thermogenesis and lipolysis and to modulate cardiac function in models of cardiovascular disease.{30104} It has also been used in rodents to study the role that β3-adrenergic receptors play in regulating anxiety-like behaviors.{30102}