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1,24-dihydroxy Vitamin D3 (hydrate)
品牌: Cayman
产品货号: 12079-500 µg
规格: 500 µg

报价:
折后价:

数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    1,24-dihydroxy Vitamin D3 (hydrate)
  • 别名:
    1α,24(R)-Dihydroxycholecalciferol|Bonalfa|Curatoderm|PRI 2191|Tacalcitol|TV 02
  • 产品描述:
    Vitamin D aids in the absorption of calcium and has central roles in bone formation and maintenance, hypertension, cancer, and immunity.{15096,19429} In addition, the active form of vitamin D, 1,25-dihydroxy vitamin D3, decreases the proliferation and increases differentiation of keratinocytes.{21611} 1,24-dihydroxy Vitamin D3 is an analog of 1,25-dihydroxy vitamin D3 which, when used in a 4 μg/g ointment, safely and effectively suppresses psoriasis.{21613} It also is effective at increasing the time interval between phototherapy cycles when ultraviolet light is used for psoriasis.{21615} 1,24-dihydroxy Vitamin D3 inhibits the growth of both normal and psoriatic human keratinocytes (IC50 ~ 10 nM) via the vitamin D receptor.{21614} It also suppresses the production of RANTES and IL-8 by human dermal fibroblasts and reduces cutaneous lymphocyte-associated antigen on CD4+ T cells, impairing migration and skin infiltration.{21612,21610}
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  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    434.7
  • 产品形式:
    A crystalline solid
  • 存储溶液:
  • 有效期:
    1460
  • 产地:
    美国
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  • 纯度:
    ≥98%
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  • CAS号:
    93129-94-3
  • 分子式:
    C27H44O3 • H2O
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