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Somatostatin-28 (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
品牌: Cayman
产品货号: 24991
规格: 500 µg

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数量: - +
产品详情
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  • 产品名称:
    Somatostatin-28 (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
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  • 产品描述:
    Somatostatin-28 is a cyclic neuropeptide hormone that has a role in endocrine regulation.{42021} It is a somatostatin (SST) receptor agonist that binds to SST1, SST2, SST3, SST4, and SST5 (IC50s = 0.60, 0.12, 0.22, 0.83, and 0.41 nM, respectively, in CCL39 cells expressing human recombinant receptors).{42022} It inhibits cAMP accumulation induced by forskolin (Item No. 11018) in CCL39 cells expressing human recombinant SST1, SST2, SST3, SST4, and SST5 (EC50s = 5.13, 1.91, 6.46, 2.95, and 3.55 nM, respectively).{42023} Somatostatin-28 stimulates growth hormone (GH) release from primary porcine pituitary cells when used at a concentration of 1 fM.{42024} It inhibits acid secretion induced by gastrin I (Item No. 24457) and IBMX (Item No. 13347) in isolated rat gastric mucosa (EC50s = 27 and 252 nM, respectively).{42025} In vivo, somatostatin-28 dose-dependently increases basal and pentagastrin-induced gastric acid secretion in rats.{42026}
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  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    3148.6
  • 产品形式:
    A lyophilized powder
  • 存储溶液:
  • 有效期:
    1460
  • 产地:
    美国
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  • 纯度:
    ≥95%
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  • 分子式:
    C137H207N41O39S3 • XCF3COOH
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