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Glucose-dependent Insulinotropic Polypeptide (human) (trifluoroacetate salt)
品牌: Cayman
产品货号: 25004
规格: 1 mg

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数量: - +
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  • 产品名称:
    Glucose-dependent Insulinotropic Polypeptide (human) (trifluoroacetate salt)
  • 别名:
    Gastric Inhibitory Peptide|GIP
  • 产品描述:
    Glucose-dependent Insulinotropic Polypeptide (GIP) (human) is an endogenous 42-amino acid peptide incretin hormone that induces insulin secretion in response to glucose.{41496} It belongs to the secretin/glucagon superfamily of peptides, which includes secretin (Item Nos. 24990 | 24561), glucagon (Item No. 24204), glucagon-like peptide-1 (GLP-1; Item No. 24460), GLP-2 (Item No. 24414), and pituitary adenylate cyclase-activating polypeptide (PACAP; Item Nos. 24769 | 24770).{36556} GIP is a GIP receptor agonist that binds to rat recombinant GIP receptors expressed in CHO-K1 cells (IC50 = 3.2 nM) and increases cAMP accumulation (EC50 = 377 pM).{42027} It stimulates insulin secretion from BRIN-BD11 rat pancreatic β-cells when used at a concentration of 10 nM.{42028} GIP (1 pmol/min per 100 g) decreases blood glucose level and increases plasma insulin level in rats following glucose challenge.{42027} It also decreases plasma glucose level and increases insulin level in ob/ob mice following glucose challenge when administered at a dose of 25 nmol/kg.{42029}
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  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    4983.5
  • 产品形式:
    A lyophilized powder
  • 存储溶液:
  • 有效期:
    1460
  • 产地:
    美国
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  • 纯度:
    ≥95%
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  • 分子式:
    C226H338N60O66S • XCF3COOH
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