产品描述:
Regadenoson is a selective, short-acting adenosine A2A receptor agonist (Ki = 1.1 nM for pig striatum A2A receptor).{30539,30542} It increases coronary blood flow 3.4- to 3.8-fold with a half-time to reversal of 1.9-2.6 minutes in open-chest anesthetized pigs.{30539} Regadenoson is used to induce hyperemia (increased blood flow), particularly in the context of myocardial perfusion imaging.{30537,30541} It has also been found to increase the delivery of compounds to the central nervous system through the blood-brain barrier in animals.{30538,30540}