产品描述:
Bavachinin is a natural flavanone first isolated from seeds of P. corylifolia. It is a pan-PPAR agonist (EC50s = 4.0, 8.1, and 0.74 µM for PPARα, β/δ, and γ, respectively).{30858} Bavachinin has synergistic effects when combined with thiazolidinediones or fibrates. It lowers glucose and triacylglycerol levels in db/db mice without inducing weight gain or hepatotoxicity.{30858} Bavachinin also has actions that block allergic inflammation, angiogenesis, and Aβ42 aggregation in vitro.{31775,33151,33152}