产品描述:
Fludioxonil is a phenylpyrrole fungicide.{42436} It inhibits the growth of B. cinerea isolates from strawberry and blackberry crops (EC50s = 0.06-0.38 mg/L).{42437} Fludioxonil also inhibits the growth of S. cerevisiae AF293 and C. albicans IFO1385 in a concentration-dependent manner.{42436,42438} It is an estrogen receptor α (ERα) agonist (EC50 = 3.7 μM in a yeast reporter assay) that induces expression of the oncogenic microRNA miR-21, inhibits estradiol-induced proliferation, and reduces cell motility of MCF-7 breast cancer cells in vitro.{42439} Formulations containing fludioxonil have been used as fungicides in agricultural, aquatic, commercial, industrial, and residential areas.