产品描述:
Ionotropic glutamate receptors can be divided into three groups, depending on whether they are activated by α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), kainate, or N-methyl-D-aspartate (NMDA). NBQX is a water-soluble receptor antagonist which targets both AMPA- and kainate-sensitive glutamate receptors (IC50 = 0.15 and 4.8 µM, respectively).{23787} It does not block the NMDA-sensitive glutamate receptor (IC50 = ≥ 90 µM).{23787} NBQX can be used in isolated neurons, tissues, or in vivo.{23788,23789,20019,23782}