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ACTH (1-10) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
品牌: Cayman
产品货号: 27105-1 mg
规格: 1 mg

报价:
折后价:

数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    ACTH (1-10) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
  • 别名:
    Adrenocorticotropic Hormone (1-10)|Corticotropin (1-10)
  • 产品描述:
    Adrenocorticotropic hormone (ACTH) (1-10) is an N-terminal peptide fragment of ACTH, a peptide hormone produced by the anterior pituitary gland that is involved in the biological stress response.{49033,45140} The amino acid sequence of ACTH (1-10) is common to ACTH and α-melanocyte stimulating hormone.{45139} ACTH (1-10) is an agonist of melanocortin receptor 3 (MC3R) and MC4R (EC50s = 2.6 and 200 nM, respectively, for the recombinant human receptors) and increases adenylate cyclase activity in HEK293 cells expressing human recombinant MC1R (EC50 = 25 nM).{45139,49034} It inhibits extinction of the conditioned avoidance response rats in shuttle-box and pole-jumping tests when administered at doses of 10 and greater than 20 μg, respectively.{49033,49035} Intracerebroventricular injection of ACTH (1-10) reduces the incidence and severity of cold-restraint stress-induced gastric lesions in rats.{49036}
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  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    1299.4
  • 产品形式:
    A solid
  • 存储溶液:
  • 有效期:
    1460
  • 产地:
    美国
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  • 纯度:
    ≥95%
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  • 分子式:
    C59H78N16O16S • XCF3COOH
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