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Adrenorphin (human, mouse, rat, bovine) (trifluoroacetate salt)
品牌： Cayman
产品货号： 35826-10 mg
规格： 10 mg

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数量： - +
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  • 产品名称:
    Adrenorphin (human, mouse, rat, bovine) (trifluoroacetate salt)
  • 别名:
    Met5-Enkephalin-Arg6-Arg7-Val8-NH2|Metorphamide|Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-NH2
  • 产品描述:
    Adrenorphin is an octapeptide agonist of μ-opioid receptors that is involved in nociception.{51269,51270} It is a C-terminally amidated cleavage product corresponding to amino acids 210-218 of human proenkephalin A. It was originally found in a human pheochromocytoma but has also been found in the rat adrenal medulla and the rat olfactory bulb, hypothalamus, and striatum, among other brain regions.{51269,51271,51272} Adrenorphin selectively binds to μ-opioid receptors over κ- and δ-opioid receptors (Kis = 0.12, 0.248, and 2.65 nM, respectively, in a radioligand binding assay).{51269} Intracerebroventricular administration of adrenorphin (6.1 nmol/animal) increases the latency to paw licking in the hot plate test in mice, indicating analgesic activity, an effect that can be reduced by the non-selective opioid receptor antagonist naloxone.{51270} It also induces respiratory depression in mice and rabbits (ED50s = 6 and 71.1 nmol/animal, respectively).
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  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    952.1
  • 产品形式:
    A solid
  • 存储溶液:
  • 有效期:
    1460
  • 产地:
    美国
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  • 纯度:
    ≥98%
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  • 分子式:
    C44H69N15O9 • XCF3COOH
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