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产品名称:
C-Dim 12
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别名:
3,3'-[(4-Chlorophenyl)methylene]bis[1H-indole]
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产品描述:
Displays neuroprotective activity in a mouse model of progressive neurodegeneration
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同种型:
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产品浓度:
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表达系统:
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阳性对照:
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保存温度:
-20ºC
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运输温度:
Shipped Ambient
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细胞定位:
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预期分子量:
356.9
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产品形式:
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存储溶液:
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有效期:
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产地:
加拿大
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外观:
Orange powder
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生产商:
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功能与背景:
C-DIM 12 is a nurr1 activator that inhibits bladder cancer growth (1,2). It also inhibits NF-κB and cytokine expression in microglial cells by stabilizing nuclear corepressor proteins, which reduces binding of p65 to inflammatory gene promoters (3). It displays neuroprotective activity in a mouse Parkinson's disease models (4).
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纯度:
>98% (TLC); NMR (Conforms)
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生物活性:
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内毒素水平:
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来源:
Synthetic
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表达方式:
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Accession #:
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CAS号:
178946-89-9
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分子式:
C23H17ClN2
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溶解度:
May be dissolved in DMSO (35 mg/ml); or ethanol (35 mg/ml)
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PubChem CID: