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FURA-2 pentapotassium salt
品牌： Adipogen
产品货号： CDX-F0013-M001
规格： 1 mg

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折后价：

数量： - +
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  • 产品名称:
    FURA-2 pentapotassium salt
  • 别名:
    Fura-2 . 5K
  • 产品描述:
    Fura-2 pentapotassium salt is a widely used UV-excitable fluorescent calcium indicator. It is a fluorophore chelating probe for Ca2+ used widely in biological systems to analyze intracellular calcium levels. It can be used to detect calcium in cells. A diagnostic shift in the excitation spectrum from 363nm to 335nm indicates FURA-2 chelation to Ca2+. Upon calcium binding, the fluorescent excitation maximum of the indicator undergoes a blue shift from 363 nm (Ca2+-free) to 335 nm (Ca2+-saturated), while the fluorescence emission maximum is relatively unchanged at ~510 nm. Analysis of Ca2+ flux in and out of cells with Fura-2 introduces a powerful spectrographic handle to investigate and elucidate correlated biological events such as neuronal ion channel activation. A major use of Fura-2 is in drug discovery, for measuring intracellular calcium mobilization after activation of G protein-coupled receptors (GPCRs) and calcium channels. It can also be used as a zinc indicator or measuring membrane potential. Fura-2 fluorescence can be detected using flow cytometry, fluorescence microscopy, or certain fluoresence microplate readers. Fura-2 potassium salt is a cell-impermeable fluorescent probe for detection Ca2+ in a ratiometric mode. However, it may be loaded into cells via microinjection or scrape loading. Spectral data: lambdaEx 363nm, lambdaEm 512nm in water.
  • 反应种属:
  • 宿主来源:
    Synthetic
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  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
    831.99
  • 产品形式:
    solid
  • 存储溶液:
  • 有效期:
    Stable for at least 2 years after receipt when stored at -20°C.
  • 产地:
    瑞士
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  • 纯度:
    >90% (HPLC)
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  • CAS号:
    113694-64-7
  • 分子式:
    C29H22N3O14 . 5K
  • 溶解度:
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