产品描述:
5-Methycytosine is a methylated derivative of the pyrimidine base cytosine (Item No. 36219) and its presence in DNA is generally associated with reduced gene transcription.{48688,29364} Increased levels of 5-methylcytosine have been found in non-expressed and untranslated DNA sequences, and levels of 5-methylcytosine are increased on developmental genes to reduce aberrant expression in adults.{29364} 5-Methylcytosine is also found in the tRNA, mRNA, and rRNA from bacteria, archaea, and eukaryotes.{26198}