产品描述:
Quinidine is a dextrorotatory stereoisomer of Quinine with anti-malarial, anti-arrhythmic (class 1A), anti-inflammatory, anti-cancer and anti-viral properties. Quinidine acts as a blocker of voltage-gated sodium channels. Inhibition of the Nav1.5 channel is specifically involved in its anti-arrhythmic effects as a class I anti-arrhythmic agent. Quinidine also blocks certain voltage-gated potassium channels (e.g. Kv1.4, Kv4.2, hERG, among others), acts as an anti-muscarinic. Quinidine blocks alpha1-adrenoceptors (alpha1ARs) and is an inhibitor of cytochrome P450 and acetylcholinesterase.