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Ganciclovir (sodium salt)
品牌: Cayman
产品货号: 37487-25 mg
规格: 25 mg

报价:
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数量: - +
产品详情
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  • 产品名称:
    Ganciclovir (sodium salt)
  • 别名:
    2’-NDG|2'-Nor-2'-deoxyguanosine|9-(1,3-dihydroxy-2-propoxymethyl)Guanine|BW 759|DHPG|GCV|RS 21592
  • 产品描述:
    Ganciclovir is an active metabolite of the prodrug valganciclovir (Item No. 13875) and an antiviral nucleoside derivative of 2’-deoxyguanosine (Item No. 9002864).{51563,22180} It reduces human, monkey, mouse, and guinea pig CMV replication in plaque reduction assays (EC50s = 1.3-70 µM).{22180} Topical application of ganciclovir (0.15%) decreases disease severity and corneal leukocyte infiltration in a cat model of ocular feline herpesvirus-1 (FHV-1) epithelial infection.{51566} Ganciclovir (15 mg/kg) prevents allograft histologic injury and natural killer (NK) and myeloid cell infiltration in a mouse model of murine CMV infection with renal transplantation.{51565} It induces tumor regression in a K-BALB murine sarcoma model using a mixed population of cells, which are positive or negative for expression of the gene encoding herpes simplex virus (HSV) thymidine kinase (TK).{51564} Formulations containing ganciclovir have been used in the treatment and prevention of CMV infections.
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  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    277.2
  • 产品形式:
    A solid
  • 存储溶液:
  • 有效期:
    1460
  • 产地:
    美国
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  • 纯度:
    ≥98%
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  • CAS号:
    107910-75-8
  • 分子式:
    C9H12N5O4 • Na
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