产品描述:
Sulfo-SMCC is a water-soluble protein cross-linking reagent that contains an anime-reactive sulfo-N-hydroxysuccinimide (sulfo-NHS) ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins.{69720,69721} It has been used to conjugate anti-programmed cell death ligand 1 (PD-L1) antibodies to the surface of platelets to induce antitumor immunity in xenograft models, as well as to conjugate Golgi-targeting peptides to platelet microparticle-mimetic nanoplatforms for the delivery of all-trans retinoic acid (Item No. 11017) to isolated human synovial fibroblasts from patients with rheumatoid arthritis.