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Chondroitin Sulfate A (sodium salt)
品牌: Cayman
产品货号: 37801-5 g
规格: 5 g

报价:
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数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    Chondroitin Sulfate A (sodium salt)
  • 别名:
    Chondroitin-4-sulfate|CSA
  • 产品描述:
    Chondroitin sulfate A (CSA) is a glycosaminoglycan.{52864} It can be biosynthetically polymerized in a variety of species and serve as structural components in cartilage when tethered to extracellular proteins. CSA (0.5 or 1 mg/ml) reduces LPS-induced decreases in viability, as well as LPS-induced increases in Tnf-α, Il-1β, Il-6, Ifn-γ, inducible nitric oxide synthase (iNOS), and matrix metalloproteinase-1 (Mmp-1) levels, nitric oxide (NO) production, and NF-κB activity in primary mouse chondrocytes.{67738} Extracellular CSA is required for P. falciparum-infected erythrocytes to adhere to the endothelium in the brain and placenta and avoid immune detection.{67739} In vivo, CSA (30, 60, or 120 mg/kg per day) reduces arthritis incidence and joint swelling, decreases 8-isoprostane levels in articular cartilage cells, and increases IκBα levels in cartilage cell cytoplasm in a mouse model of collagen-induced arthritis.{67740}
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  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    499.4
  • 产品形式:
    A solid
  • 存储溶液:
  • 有效期:
    1460
  • 产地:
    美国
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  • CAS号:
    9082-07-9
  • 分子式:
    C14H22NO15S • Na
  • 溶解度:
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