产品描述:
Heptafluorobutyric acid is a perfluoroalkyl substance (PFAS).{67175} Chronic topical administration of heptafluorobutyric acid (25 µl of a 3.75-15% v/v solution) on the ear increases liver and kidney weight in mice. It induces multifocal hepatocyte necrosis and centrilobular hepatocyte hypertrophy when administered topically at a concentration of 7.5% v/v. Heptafluorobutyric acid (15% v/v) increases serum cholesterol and alkaline phosphatase (ALP) levels and decreases serum urea nitrogen levels. It has been found in marine life and as a contaminant in surface water.{66209,67174} Formulations containing heptafluorobutyric acid have been used as ion pair reagents for reverse-phase HPLC and in the synthesis and solubilization of proteins and peptides.