产品描述:
(±)-Climbazole is an imidazole antifungal agent.{47625} It inhibits the growth of C. albicans (MIC = 0.29 μg/ml), as well as clinical isolates of M. pachydermatis (MICs = M. furfur (MICs = in vitro.{48240,48241,47626} It also reduces the size of Malassezia populations on the skin of naturally infected dogs when used at a dose of 2% in shampoo.{47625} (±)-Climbazole (80 mg/kg) increases the levels of cytochrome P450 in rat liver.{48242} Formulations containing climbazole have been used in the treatment of dandruff.