产品描述:
Chlorphenesin carbamate is a muscle relaxant.{67532} It decreases the dorsal root potential induced by a current-stimulated ventral root, as well as L-glutamate-induced motor neuron discharges, in isolated frog spinal cords when used at a concentration of 1 mM. In vivo, chlorphenesin carbamate (50 mg/kg) reduces the amplitude of polysynaptic responses in ipsilateral ventral root L5 induced by electrical stimulation of dorsal root L5 in spinalized rats.{67533} It decreases monosynaptic signal transfer from primary afferent fibers to motor neurons in the same animals at the same dose. Formulations containing chlorphenesin carbamate have been used in the treatment of post-surgical pain, acute inflammation, and as a muscle relaxant in veterinary applications.