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产品名称:
Muscone
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别名:
3-Methyl-cyclopentadecanone (racemic)
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产品描述:
Antiinflammatory and Neuroprotective activity
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反应种属:
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实验应用:
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靶标/特异性:
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同种型:
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推荐稀释度:
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免疫原:
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免疫原种属:
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克隆性:
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纯化方式:
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偶联:
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产品浓度:
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表达系统:
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阳性对照:
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保存温度:
-20ºC
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运输温度:
Shipped Ambient
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细胞定位:
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预期分子量:
238.4
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产品形式:
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存储溶液:
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有效期:
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产地:
加拿大
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外观:
Colorless oil
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生产商:
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功能与背景:
Muscone is a macrocyclic ketone found naturally in a glandular secretion of the musk deer which acts at human odorant receptor OR5AN1 and is used in perfumes(1). It suppresses inflammatory responses and neuronal damage in various models including a rat model of cervical spondylotic myelopathy (2) and relieves inflammatory pain acting via the NOX4/JAK2-STAT3 and NLRP3 inflammasome pathway (3). In the cardiovascular system it alleviates myocardial ischemia-reperfusion injury (4) and improves cardiac function in mice after myocardial infarction (5) via enhancement of angiogenesis (6).
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URL:
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产品特点:
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纯度:
>98% (TLC); NMR (Conforms)
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生物活性:
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内毒素水平:
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来源:
Synthetic
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表达方式:
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Accession #:
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CAS号:
541-91-3
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分子式:
C16H30O
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溶解度:
May be dissolved in DMSO (35 mg/ml); or Ethanol (35 mg/ml)
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PubChem CID: