产品描述:
BI-639667 is a chemokine (C-C motif) receptor 1 (CCR1) antagonist.{49890} It inhibits calcium flux induced by chemokine (C-C motif) ligand 3 (CCL3) in cells expressing CCR1 (IC50 = 2 nM). BI-639667 also inhibits RANTES-induced chemotaxis in THP-1 cells (IC50 = 2 nM).