产品描述:
Hydroquinidine is an alkaloid and derivative of the antiarrhythmic agent quinidine that decreases heart rate variability.{39149,39148,39151} It increases the length of the sinus cycle and prolongs QRS duration and ventricular repolarization in anesthetized dogs.{39148} It has also been imprinted on microspheres as a pseudo-template molecule for recognition of cinchona alkaloids.{39151} Formulations containing hydroquinidine have been studied for use in treatment of Brugada syndrome, which is a genetic disorder characterized by ventricular fibrillation and a risk of sudden death.{39150}