-
产品名称:
Seriniquinone
-
别名:
Dinaphtho[2,3-b:2',3'-d]thiophene-5,7,12,13(5aH,12bH)-tetraone
-
产品描述:
Seriniquinone is a potent cytotoxic and melanoma-selective anticancer agent. Upon cellular treatment and based on the compounds fluorescent nature it was found localized in the endoplasmic reticulum. Seriniquinone inhibits cell proliferation marked by autophagocytosis and induces cell death due to caspase-9 dependent apoptosis. Mode of action studies suggest that it specifically targets a skin protective antimicrobial peptide dermcidin (DCD), whose role as a cancer-protective protein has been recently recognized.
-
反应种属:
-
宿主来源:
Synthetic. Originally isolated from marine bacterium Serinicoccus sp. strain CNJ927.
-
实验应用:
-
靶标/特异性:
-
同种型:
-
推荐稀释度:
-
免疫原:
-
免疫原种属:
-
克隆性:
-
克隆号:
-
纯化方式:
-
偶联:
-
产品浓度:
-
表达系统:
-
阳性对照:
-
保存温度:
-20°C
-
运输温度:
Ambient
-
细胞定位:
-
预期分子量:
344.3
-
产品形式:
solid
-
存储溶液:
-
有效期:
Stable for at least 1 year after receipt when stored at -20°C.Stock solutions are stable for at least 3 months when stored at -20°C.
-
产地:
瑞士
-
外观:
-
生产商:
-
功能与背景:
-
URL:
-
灵敏度:
-
检测范围:
-
检测方法:
-
样本类型:
-
产品特点:
-
纯度:
>99% (HPLC)
-
生物活性:
-
内毒素水平:
-
来源:
-
表达方式:
-
Accession #:
-
CAS号:
22200-69-7
-
分子式:
C20H8O4S
-
溶解度:
-
PubChem CID: