产品描述:
BIX 02565 is a novel ribosomal S6 kinase 2 (RSK2) inhibitor with an IC50 of 1.1nM. BIX 02565 also has inhibitory effects on LRRK2, RET, CLK2, FLT3 and PDGFR. BIX 02565 can be used in vitro and in vivo to explore the role of RSK as a target for the treatment heart failure.