产品描述:
Cell permeable dimeric dilactone macrolide [1]. Cytotoxic compound [1, 2, 7]. Specific actin filament (F-actin) inhibitor. Disrupts the actin cytoskeleton by sequestering actin dimers and rapidly severing actin filaments (F-actin) [3, 5, 7, 8]. Depolymerizes actin filaments (F-actin) [6]. Antifungal [4]. Apoptosis inducer [9]. Alterates the actin cytoskeleton of GH4 cells and inhibits insulin-increased prolactin gene transcription [10].