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IAXO-101 (CD14/TLR4 Antagonist) (synthetic)
品牌: Adipogen
产品货号: IAX-600-001-M001
规格: 1 mg

报价:
折后价:

数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    IAXO-101 (CD14/TLR4 Antagonist) (synthetic)
  • 别名:
    Methyl 6-deoxy-6-N-dimethyl-N-cyclopentylammonium-2,3-di-O-tetradecyl-alpha-D-glucopyranoside iodide
  • 产品描述:
    CD14/TLR4 antagonist. Inhibitor of sterile inflammation. Synthetic TLR4/CD14 ligand with TLR4 modulating activities in vitro, and conferring protection against TLR4/CD14-mediated tissue damage and inflammation in vivo. Useful to explore CD14- dependent and TLR4-independent pathways and TLR4 activation by endogenous ligands (e.g. hyaluronic acid oligosaccharides, oxLDL, HMGB1) in sterile inflammation. Shown to inhibit neuropathic pain, secondary necrosis of acute drug-induced liver failure and vascular inflammation, and abdominal aortic aneurysm by blocking non-hematopoietic TLR4 signaling. Useful tool, where inhibition of sterile (auto-) inflammation is desired, without compromising TLR4’s key role in the defense of pathogens.
  • 反应种属:
  • 宿主来源:
    Synthetic.
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  • 阳性对照:
  • 保存温度:
    +4°C
  • 运输温度:
    Ambient
  • 细胞定位:
  • 预期分子量:
    810.02g/mol (iodide salt)
  • 产品形式:
    solid
  • 存储溶液:
  • 有效期:
    Stable for at least 1 year after receipt when stored at +4°C.
  • 产地:
    瑞士
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  • 纯度:
    >98% (TLC)
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  • CAS号:
    1202388-64-4
  • 分子式:
    C42H84INO5
  • 溶解度:
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