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sPLA2 (Type IIA) Inhibitor Screening Assay Kit
品牌: Cayman
产品货号: 702470
规格: 384 Well

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数量: - +
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  • 产品名称:
    sPLA2 (Type IIA) Inhibitor Screening Assay Kit
  • 别名:
    GIIC sPLA2|Group IIA Phospholipase A2|Non-Pancreatic Secretory Phospholipase A2|Phosphatidylcholine 2-Acylhydrolase 2A|Phospholipase A2, Membrane Associated|PLA2G2A|Secretory Phospholipase A2 (Group IIA)|sPLA2-IIA
  • 产品描述:
    Cayman’s sPLA2 (Type IIA) Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of human sPLA2 type IIA, a phospholipase that preferentially hydrolyzes PG and PE. The assay uses diheptanoyl thio-PE, a sulfur-containing analog of PE as a substrate. Upon hydrolysis by sPLA2 type IIA at the sn-2 position, the free thiol can be detected by the sPLA2 Assay Probe. This results in a product that can be easily quantified by measuring absorbance at a wavelength of 410 nm. A potent and reversible inhibitor, LY315920 (included in this kit as sPLA2 Control Inhibitor), inhibits the enzyme with an average IC50 value of approximately 22 nM.
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    -80
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    -80
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  • 有效期:
    365
  • 产地:
    美国
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