产品描述:
Colupulone is a β-acid that has been found in H. lupulus and has diverse biological activities.{58789,58790,58791} It activates the pregnane X receptor (PXR) in a reporter assay when used at concentrations of 1, 3, and 10 µM.{58789} Dietary administration of colupulone (0.18% w/w) induces hepatic cytochrome P450 (CYP) isoform 3A (CYP3A) activity in mice.{58790} It also decreases serum glucose levels in non-diabetic mice and increases serum glucose levels in db/db mice.{58791}