产品描述:
Ingenol is a diterpenoid related to phorbol, derived from the milkweed plant E. peplus.{771} It is a protein kinase C activator that displays a Ki value of 30 μM and an ED50 value of 27 μM in vitro.{23438,23437} Most ingenol esters are tumor-promoting.{17808} However, ingenol mebutate possesses anti-tumor activity when used topically for actinic keratosis.{21836}