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折扣/货期| 货号：10009746 | 规格：50 µg | 目录价：￥6384 |
产品详情
产品名称:
PTEN (human recombinant)
别名:
MMAC1|Phosphatase and Tensin Homology on Chromosome 10|Phosphatidylinositol 3-phosphatase|TEP1
产品描述:
Phosphatase and tensin homology on chromosome 10 (PTEN) functions as a key regulatory enzyme in many signal transduction pathways by dephosphorylating proteins and lipids such as AKT and phosphatidylinositol 3,4,5-trisphosphate (PIP3). PTEN interacts with many other proteins to regulate cell division and migration, as well as promoting apoptosis when necessary.{13065} Mutation of PTEN results in many human cancers including melanoma and prostate carcinoma, making PTEN an important tumor suppressor.{12235,13040} PTEN is expressed in almost all tissues of the body as a 403 amino acid protein with an estimated molecular weight of 47 kDa, however the actual migration observed on western blot may vary among distinct samples.{13064}
保存温度:
-80
运输温度:
-80
产品形式:
50 mM Tris-HCl, pH 8.0, 100 mM sodium chloride, 5 mM DTT, and 20% glycerol
有效期:
180
纯度:
≥95% estimated by SDS-PAGE
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