货号:702470 | 规格:384 Well | 目录价:¥6986 |
产品详情
产品名称:
sPLA2 (Type IIA) Inhibitor Screening Assay Kit
别名:
GIIC sPLA2|Group IIA Phospholipase A2|Non-Pancreatic Secretory Phospholipase A2|Phosphatidylcholine 2-Acylhydrolase 2A|Phospholipase A2, Membrane Associated|PLA2G2A|Secretory Phospholipase A2 (Group IIA)|sPLA2-IIA
产品描述:
Cayman’s sPLA2 (Type IIA) Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of human sPLA2 type IIA, a phospholipase that preferentially hydrolyzes PG and PE. The assay uses diheptanoyl thio-PE, a sulfur-containing analog of PE as a substrate. Upon hydrolysis by sPLA2 type IIA at the sn-2 position, the free thiol can be detected by the sPLA2 Assay Probe. This results in a product that can be easily quantified by measuring absorbance at a wavelength of 410 nm. A potent and reversible inhibitor, LY315920 (included in this kit as sPLA2 Control Inhibitor), inhibits the enzyme with an average IC50 value of approximately 22 nM.
保存温度:
-80
运输温度:
-80
有效期:
365
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