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折扣/货期| 货号：38492 | 规格：3.6 mg | 目录价：￥3710 |
产品详情
产品名称:
TNP-ATP (sodium salt)
产品描述:
TNP-ATP is a derivative of ATP and an antagonist of the purinergic P2Y1, P2X3, and P2X2/3 receptors (IC50s = 6, 0.9, and 7 nM, respectively, in HEK293 cells expressing the human receptors).{36447} It is selective for these receptors over the purinergic P2X2, P2X4, and P2X7 receptors (IC50s = 2, 15.2, and >30 µM, respectively, in HEK293 cells expressing the human receptors). TNP-ATP decreases acetic acid-induced calcium flux in 1321N1 cells expressing the P2X3 and P2X2/3 receptors (IC50s = 100 and 62 nM, respectively).{36448} It reduces acetic acid-induced writhing in a mouse model of visceral pain (ED50 = 6.35 µmol/kg). It displays an emission maximum of 547 nm upon excitation at 403 nm, and its relative fluorescence increases four-fold when bound to insulin-degrading enzyme (IDE) and emission shifts to 538 nm.{36449}
保存温度:
-80
运输温度:
-80
预期分子量:
806.2
产品形式:
A solution in water
有效期:
730
纯度:
≥95%
分子式:
C16H13N8O19P3 • 4Na
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