TRAF5 Monoclonal Antibody (Clone 55A219)-单抗-ELISA_抗体_蛋白_核苷酸

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TRAF5 Monoclonal Antibody (Clone 55A219)

品牌：Cayman

官网链接

说明书

折扣/货期

货号：10873

规格：1 ea

目录价：￥6246

产品详情

产品名称:

TRAF5 Monoclonal Antibody (Clone 55A219)

产品描述:

Tumor necrosis factor (TNF)-induced signaling is mediated through association of TNF receptor (TNFR) with adaptor proteins, such as TNF receptor-associated factors (TRAFs). TRAFs form a family of cytoplasmic adapter proteins that mediate signal transduction from many members of the TNF-receptor superfamily (e.g., RANK, CD30, CD40, etc.) and the interleukin-1 receptor. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. Recent molecular cloning studies have led to identification of seven TRAFs (TRAF1-TRAF7).{19431,18761,19383,19384,19385} Human TRAF5 is a 557-amino acid protein. TRAF5 is implicated in NF-kB and c-Jun NH(2)-terminal kinase/stress-activated protein kinase activation by members of the TNF receptor superfamily, including CD27, CD30, CD40, and lymphotoxin-β receptor. Targeted disruption of TRAF5 gene causes defects in CD40-CD27 mediated lymphocyte activation.{19385}

宿主来源:

Mouse

实验应用:

免疫原:

fusion protein corresponding to amino acids 77-186 of human TRAF5

克隆号:

55A219

保存温度:

-20

运输温度:

-20

产品形式: