品牌:Mabtech
中文名称:猴IFN-γ酶联免疫斑点检测试剂盒
货号:3421M-4AST
应用:ELISpot
反应种属:小鼠
组分:Biotinylated detection mAb (7-B6-1)
Streptavidin-ALP
anti-CD3 mAb
Substrate (BCIP/NBT-plus)
2 Pre-coated strip clear plates (mAb MT126L)
规格:2 plates,10 plates
IFN-γ:干扰素-γ (IFN-γ, 也称 IFN-gamma, IFN-g和Interferon-gamma)主要由活化的T细胞和NK细胞产生。它是一种激活巨噬细胞和内皮细胞的促炎细胞因子,也通过影响APC、T和B细胞来调节免疫反应。辅助T细胞和细胞毒性T细胞产生IF ELISpot N-γ是th1型表型的标志,因此,大量IFN-γ的产生通常与宿主对胞内病原体的有效防御有关。
参考文献:
Roques, P., et al. (2017). Attenuated and vectored vaccines protect nonhuman primates against Chikungunya virus. JCI Insight.
Sauermann, U., et al. (2017). Vector order determines protection against pathogenic simian immunodeficiency virus infection in a triple component vaccine by balancing CD4 and CD8 T-cell responses. Journal of virology.
Sharpe, S. A., et al. (2018). Refinement and reduction through application of a quantitative score system for estimation of TB-induced disease burden using computed tomography. Lab Anim.
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