货号:JAI-KOG-HS10E | 规格:1 Kit | 目录价:¥13468 |
产品详情
产品名称:
8-OHdG Check ELISA Kit (High Sensitivity)
别名:
8-hydroxy-2' -deoxyguanosine
产品描述:
8-hydroxy-2'-deoxyguanosine (8-OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals (incl. singlet oxygen and direct photodynamic action) that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer’s disease. 8-OHdG is popular as a sensitive, stable and integral marker of oxidative damage in cellular DNA and can be detected in tissue, serum, urine and other biomaterials.
靶标/特异性:
Specific for 8-OHdG. Has been tested to 8-OHdG analogues (guanosine(G),7-methyl-G, 6-SH-G, 8-Bromo-G, dA, dC, dT, dI, dU, dG, O6-methyl-dG,8-OHdA, guanine(Gua),O6-methyl-Gua, 8-OH-Gua, uric acid, urea, creatine, creatinine, 8-sulfhydryl-G, 8-OH-G).
保存温度:
+4°C
运输温度:
BLUE ICE
有效期:
12 months after the day of manufacturing. See expiry date on ELISA Kit box.
产地:
瑞士
检测范围:
0.125 to 10 ng/mL
检测方法:
Competitive
样本类型:
Plasma, Serum, Urine
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