货号:38085-100 µl | 规格:100 µl | 目录价:¥4374 |
货号:38085-200 µl | 规格:200 µl | 目录价:¥7002 |
货号:38085 | 规格:50 µl | 目录价:¥2916 |
产品详情
产品名称:
C1 Inhibitor Polyclonal Antibody
别名:
C1 Esterase Inhibitor|C1-INH|Plasma Protease C1 Inhibitor|Serine Protease Inhibitor Family G1|Serpin G1
产品描述:
Plasma protease C1 inhibitor (C1 inhibitor) is a secreted plasma glycoprotein and member of the serine protease inhibitor (SERPIN) family.{68261,68262} It is composed of an N-terminal domain and a serpin domain, which contains a reactive center loop (RCL).{68262} The RCL of C1 inhibitor mimics the target protease substrates and, upon cleavage, inactivates proteases via an irreversible covalent bond with the protease active site serine. C1 inhibitor targets several serine proteases, including complement 1r (C1r) and C1s, Factor XII, thrombin, and plasmin. It is involved in vascular permeability, extracellular matrix interactions, recognition of pathogens such as bacteria and parasites, ischemia-reperfusion injury, and transplant rejection. Knockout of the gene encoding C1 inhibitor, Serping1, increases vascular permeability in mice.{40793} Mutations in SERPING1 are associated with hereditary angioedema (HAE), and plasma levels of C1 inhibitor are increased in patients with COVID-19.{68263,68264} Formulations containing recombinant human C1 inhibitor have been used in the prophylaxis of angioedema attacks. Cayman’s C1 Inhibitor Polyclonal Antibody can be used for ELISA, immunohistochemistry paraffin (IHC-P), and Western blot (WB) applications. The antibody recognizes C1 inhibitor at 56 kDa from human samples.
宿主来源:
Rabbit
实验应用:
WB,IHC-P, ELISA
同种型:
IgG
免疫原:
Recombinant human C1 inhibitor
保存温度:
-20
运输温度:
-20
产品形式:
50, 100, or 200 µl of antigen affinity-purified polyclonal antibody
有效期:
365
您可能感兴趣的产品
SARS-CoV-2 (COVID-19) nsp1 antibody
货号:GTX135612-S
Synapsin II antibody
货号:GTX135310-S
DLST antibody
货号:GTX134855-S
IGF2BP1 antibody
货号:GTX134816-S
SMCR8 antibody
货号:GTX134785-S
3-Methoxytyramine antibody
货号:GTX134712-S
Estrogen Receptor beta antibody
货号:GTX134663-S
Caspase 1 p10 subunit antibody
货号:GTX134551-S
促销活动