C1 Inhibitor Polyclonal Antibody-多抗-ELISA_抗体_蛋白_核苷酸_试剂盒-深圳欣博盛生物科技有限公司

首页产品中心多抗

C1 Inhibitor Polyclonal Antibody

品牌：Cayman

官网链接

说明书

折扣/货期

货号：38085-100 µl	规格：100 µl	目录价：￥4374
货号：38085-200 µl	规格：200 µl	目录价：￥7002
货号：38085	规格：50 µl	目录价：￥2916

产品详情

产品名称:

C1 Inhibitor Polyclonal Antibody

别名:

C1 Esterase Inhibitor|C1-INH|Plasma Protease C1 Inhibitor|Serine Protease Inhibitor Family G1|Serpin G1

产品描述:

Plasma protease C1 inhibitor (C1 inhibitor) is a secreted plasma glycoprotein and member of the serine protease inhibitor (SERPIN) family.{68261,68262} It is composed of an N-terminal domain and a serpin domain, which contains a reactive center loop (RCL).{68262} The RCL of C1 inhibitor mimics the target protease substrates and, upon cleavage, inactivates proteases via an irreversible covalent bond with the protease active site serine. C1 inhibitor targets several serine proteases, including complement 1r (C1r) and C1s, Factor XII, thrombin, and plasmin. It is involved in vascular permeability, extracellular matrix interactions, recognition of pathogens such as bacteria and parasites, ischemia-reperfusion injury, and transplant rejection. Knockout of the gene encoding C1 inhibitor, Serping1, increases vascular permeability in mice.{40793} Mutations in SERPING1 are associated with hereditary angioedema (HAE), and plasma levels of C1 inhibitor are increased in patients with COVID-19.{68263,68264} Formulations containing recombinant human C1 inhibitor have been used in the prophylaxis of angioedema attacks. Cayman’s C1 Inhibitor Polyclonal Antibody can be used for ELISA, immunohistochemistry paraffin (IHC-P), and Western blot (WB) applications. The antibody recognizes C1 inhibitor at 56 kDa from human samples.

宿主来源:

Rabbit

实验应用:

WB,IHC-P, ELISA

同种型:

IgG

免疫原:

Recombinant human C1 inhibitor

保存温度:

-20

运输温度:

-20