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折扣/货期| 货号：33948-100 µl | 规格：100 µl | 目录价：￥2952 |
| 货号：33948-200 µl | 规格：200 µl | 目录价：￥3924 |
| 货号：33948 | 规格：50 µl | 目录价：￥1962 |
产品详情
产品名称:
Interleukin-9 Polyclonal Antibody
别名:
Cytokine P40|HP40|IL-9|T cell Growth Factor P40
产品描述:
Interleukin-9 (IL-9) is a T helper 2 (Th2) type cytokine with various roles in immune regulation and inflammatory disease.{63344,63345} It is expressed in effector T cells, mast cells, neutrophils, eosinophils, and innate lymphoid cells in response to activation of various transcription factors, including NF-κB and nuclear factor of activated T cells (NFAT), and functions through the IL-9 receptor to induce signaling via STAT pathways and cell type-specific immune responses.{63344,63345,63346} IL9 expression is increased in patients with asthma, and immunization with an anti-IL-9 antibody inhibits airway hyperresponsiveness in a mouse model of the disease. Antibody-based suppression of IL-9 also inhibits eosinophilia in various mouse models. IL-9 has both tumor suppressive and tumorigenic activities, enhancing T cell-mediated antitumor responses in colon cancer and promoting cell survival and multidrug resistance in diffuse large B cell lymphoma (DLBCL).{63347} Cayman’s IL-9 Polyclonal Antibody can be used for immunohistochemistry (IHC) or Western blot (WB) applications. The predicted size of IL-9 is 15 kDa and this antibody recognizes IL-9 at an observed band size of 17 kDa from mouse samples.
宿主来源:
Rabbit
实验应用:
WB, IHC
同种型:
IgG
免疫原:
Synthetic peptide from the N-terminal region of the mouse IL9 expressed in rabbit
保存温度:
-80
运输温度:
-80
产品形式:
50, 100, or 200 µl of protein A and antigen affinity-purified polyclonal antibody
有效期:
365
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