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折扣/货期| 货号：AG-40B-0065T-C050 | 规格：50 ug | 目录价：￥4200 |
产品详情
产品名称:
CD24 (mouse):Fc (human) (rec.)
别名:
M1/69-J11D Heat Stable Antigen; Nectadrin; Lymphocyte Antigen 52; X62 Heat Stable Antigen (HSA); Ly-52
产品描述:
CD24 is a highly glycosylated protein expressed as glycosyl-phosphatidyl-inositol (GPI) anchored molecule. It is widely expressed, mainly on T cells, B cells and is upregulated in numerous types of cancers. It has costimulatory activity for antigen specific T cell responses. Polymorphisms of human CD24 are associated with several autoimmune diseases. Recently, a new role as negative regulator of the immune response has been reported. CD24-deficient mice are more sensitive to inflammatory responses. CD24 together with the membrane protein SIGLEC interacts with danger-associated molecular patterns (DAMPs), such as HMGB1, HSP90 or HSP70. CD24/SIGLEC complex may differentially regulate the host response to DAMPs and PAMPs (pathogen-associated molecular patterns).
宿主来源:
HEK 293 cells
产品浓度:
1mg/ml after reconstitution
保存温度:
-20°C
运输温度:
BLUE ICE
预期分子量:
~40-50kDa (SDS-PAGE)
产品形式:
solid
存储溶液:
Lyophilized. Contains PBS.
有效期:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>90% (SDS-PAGE)
内毒素水平:
<0.06EU/µg purified protein (LAL test; Lonza).
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