CD25/Interleukin-2Rα Monoclonal Antibody (PE) (Clone 143-13)-单抗-ELISA_抗体_蛋白_核苷酸

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CD25/Interleukin-2Rα Monoclonal Antibody (PE) (Clone 143-13)

品牌：Cayman

官网链接

说明书

折扣/货期

货号：10339

规格：1 ea (100 µg)

目录价：￥4928

产品详情

产品名称:

CD25/Interleukin-2Rα Monoclonal Antibody (PE) (Clone 143-13)

别名:

产品描述:

CD25, also known as interleukin-2 receptor α (IL-2Rα), is a transmembrane glycoprotein.{60243} It is composed of two domains, D1 and D2, and associates with the CD122/IL-2β and CD132/IL-2γc subunits to form the heterotrimeric IL-2 receptor. CD25 is expressed in activated T and B cells, regulatory T cells, and lymphokine-activated killer (LAK) cells.{60244,60245,6128} Activation of IL-2R on T cells increases the expression of CD25 and leads to T cell proliferation and differentiation, as well as activation-induced T cell death.{60245,6128} ILR2A expression and CD25 protein levels in bone marrow are increased in patients with acute myeloid leukemia (AML) and associated with poor prognosis.{60245} SNPs in ILR2A and elevated serum levels of a soluble form of CD25 are associated with an increased risk of Graves' disease.{60246} Cayman’s CD25/Interleukin-2Rα Monoclonal Antibody (PE) (Clone 143-13) is composed of a CD25 monoclonal antibody conjugated to phycoerythrin (PE) and can be used for flow cytometry (FC), immunocytochemistry (ICC), and immunohistochemistry (IHC) applications.

宿主来源:

Mouse

实验应用:

(+) FC, ICC, IHC (frozen sections); (−) WB

同种型:

IgG1

克隆号:

143-13

保存温度:

-20

运输温度:

-20