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折扣/货期| 货号：AG-40A-0109-C010 | 规格：10 ug | 目录价：￥2040 |
| 货号：AG-40A-0109-C050 | 规格：50 ug | 目录价：￥4320 |
产品详情
产品名称:
FGF-23 (human):Fc (human) (rec.)
别名:
Fibroblast Growth Factor 23; Tumor-derived Hypophosphatemia-inducing Factor
产品描述:
FGF-23 (Fibroblast growth factor 23) is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) and of hyperphosphatemic familial tumoral calcinosis (HFTC).
宿主来源:
HEK 293 cells
产品浓度:
1mg/ml
保存温度:
-20°C
运输温度:
BLUE ICE
预期分子量:
~60kDa (SDS-PAGE, full-length); FGF23 is cleaved between arg179 and ser 180 (~40kDa)
产品形式:
liquid
存储溶液:
Liquid. 0.2µm-filtered solution in PBS.
有效期:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>90% (SDS-PAGE)
生物活性:
Activates ERK and FRS2alpha phosphorylation in Klotho expressing cells.
内毒素水平:
<0.1EU/µg purified protein (LAL test; Lonza).
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