官网链接
折扣/货期| 货号：AG-40B-0133-3050 | 规格：3 x 50 ug | 目录价：￥5760 |
| 货号：AG-40B-0133-C050 | 规格：50 ug | 目录价：￥2880 |
产品详情
产品名称:
Frizzled-5 (human):Fc (human) (rec.) MultiPack
别名:
FzE5; Fz-5; hFz5
产品描述:
Wnts are lipid-modified morphogens that control many processes during development, stem cell maintenance and homeostasis and their aberrant regulation has been linked to diseases in man including diabetes, neurodegeneration and cancer. Three distinct receptor families mediate Wnt signaling: Fzs, the single-pass LRP5/6 co-receptors and the atypical tyrosine kinase receptors Ror2 and Ryk. Frizzled proteins can activate canonical Wnt/beta-catenin signaling as well as non-canonical pathways (Wnt/Ca2+ pathways and planar cell polarity). The cysteine-rich domain (CRD) of the frizzled receptors situated on the extracellular part of the receptor is sufficient to bind the Wnt ligands.
宿主来源:
HEK 293 cells
靶标/特异性:
Binds to human and mouse Wnt3a.
产品浓度:
1mg/ml after reconstitution
保存温度:
-20°C
运输温度:
BLUE ICE
预期分子量:
~50kDa (SDS-PAGE)
产品形式:
solid
存储溶液:
Lyophilized. Contains PBS.
有效期:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
生物活性:
Inhibits Wnt3a activation in a stoechiometric manner.
内毒素水平:
<0.01EU/µg purified protein (LAL test).
您可能感兴趣的产品
Human UFC1 protein, His tag
货号：GTX68512-pro
Human DcR2 / CD264 protein, human IgG1 Fc and His tag (active)
货号：GTX66967-pro
Mouse CTLA4 protein, mutant mouse IgG2a Fc tag (active)
货号：GTX65784-pro
Mouse TIM-4 protein, human IgG1 Fc tag (active)
货号：GTX65783-pro
Mouse TIM-1 protein, mouse IgG2a Fc tag
货号：GTX65774-pro
Mouse CD86 protein, mouse IgG2a Fc tag
货号：GTX65769-pro
Mouse CD80 protein, mouse IgG2a Fc tag
货号：GTX65767-pro
Mouse CD74 protein, mouse IgG2a Fc tag
货号：GTX65766-pro
促销活动
精品推荐
相关产品推荐
CD134 [OX40] (mouse):Fc (human) (rec.)
货号：CHI-MF-111CD134-C100
CD279 [PD-1] (mouse):Fc (human) (rec.)
货号：CHI-MF-111PD1-C100
Semaphorin-4A (mouse):Fc (human) (rec.)
货号：CHI-MF-111SEMA4-C100
Tim-1 (mouse):Fc (human) (rec.)
货号：CHI-MF-111T1-C100
Tim-2 (mouse):Fc (human) (rec.)
货号：CHI-MF-111T2-C100
Tim-4 (mouse):Fc (human) (rec.)
货号：CHI-MF-111T4-C100
