货号:18070 | 规格:100 µg | 目录价:¥6384 |
产品详情
产品名称:
Histone H3K9Me2 Monoclonal Antibody (Clone 3C11)
别名:
Dimethylated Histone H3 Lysine 9
产品描述:
Histone H3 is a nuclear protein and a component of the nucleosome core, a basic unit of chromatin, that is essential for organizing genomic DNA in eukaryotic nuclei.{57056} It is a globular protein that contains an unstructured N-terminal tail that extends outside of the nucleosome core and is subject to various post-translational modifications (PTMs), including methylation, phosphorylation, acetylation, and citrullination.{57056,53978} Dimethylation of histone H3 at lysine 9 (H3K9Me2) is associated with transcriptional repression.{48220} Heterochromatin protein 1-α (HP1-α), HP1-β, and HP1-γ selectively bind histone H3 N-terminal peptides containing dimethylated lysine 9 over unmodified lysine 9.{20846} High nuclear levels of H3K9Me2 in tumor tissue are associated with decreased disease-specific and disease-free survival in patients with oral and oropharyngeal squamous cell carcinoma.{49115} Cayman's Histone H3K9Me2 Monoclonal Antibody (Clone 3C11) can be used for ELISA.
宿主来源:
Mouse
实验应用:
ELISA
同种型:
IgG3κ
免疫原:
Synthetic peptide from human Histone H3 aa 1-30 (di-methyl K9) conjugated to KLH
克隆号:
3C11
保存温度:
-20
运输温度:
-20
产品形式:
100 µg of Protein G-purified antibody
有效期:
1095
上一个:Histone H3 (Citrullinated R2 + R8 + R17) Monoclonal Antibody (Clone 11D3)
下一个:Histone H3K9Me2 Monoclonal Antibody (Clone 5E2)
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