货号:21827 | 规格:100 µg | 目录价:¥4760 |
产品详情
产品名称:
HLA-DR Monoclonal Antibody (Clone L243)
别名:
HLA Class II Histocompatibility Antigen DR|MHC Class II Antigen DR
产品描述:
HLA-DR is a MHC Class II cell surface receptor heterodimer composed of a 33-35 kDa α chain, a ~30 kDa β chain, and a 10-30 amino acid ligand.{33426} When the heterodimer is fully combined on the cell surface of an antigen-presenting cell, such as macrophages, B cells, and dendritic cells, they present that ligand primarily to CD-4+ T cells.{15687} This presentation coupled with the T cell response can stimulate or suppress an antibody response to that ligand.{15687} HLR-DRs have been linked to a number of autoimmune disorders such as rheumatoid arthritis, lupus, and psoriasis as well as diabetes, hepatitis, and sclerosis among a number of others.{34485,34486,34487,34488,34489,34490,34491} Cayman’s HLA-DR Monoclonal Antibody (Clone L243) detects HLA-DR with or without attached ligand. The predicated size of the HLA-DRα or HLA-DRβ subunits is ~29-30 kDa.
宿主来源:
Mouse
实验应用:
FC, ICC, IF, IHC, IP, and WB
同种型:
IgG2a
免疫原:
Human lymphoblastoid cell line (RPMI 8866)
克隆号:
L243
保存温度:
-20
运输温度:
-20
产品形式:
100 µg of protein G-purified IgG
有效期:
1095
上一个:IgG Fab (mouse) Monoclonal Antibody (Clone RMG05)
下一个:Citrullinated Vimentin Monoclonal Antibody (Clone 12G11)
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