HLA-DR Monoclonal Antibody (Clone L243)-单抗-ELISA_抗体_蛋白_核苷酸

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HLA-DR Monoclonal Antibody (Clone L243)

品牌：Cayman

官网链接

说明书

折扣/货期

货号：21827

规格：100 µg

目录价：￥4760

产品详情

产品名称:

HLA-DR Monoclonal Antibody (Clone L243)

别名:

HLA Class II Histocompatibility Antigen DR|MHC Class II Antigen DR

产品描述:

HLA-DR is a MHC Class II cell surface receptor heterodimer composed of a 33-35 kDa α chain, a ~30 kDa β chain, and a 10-30 amino acid ligand.{33426} When the heterodimer is fully combined on the cell surface of an antigen-presenting cell, such as macrophages, B cells, and dendritic cells, they present that ligand primarily to CD-4+ T cells.{15687} This presentation coupled with the T cell response can stimulate or suppress an antibody response to that ligand.{15687} HLR-DRs have been linked to a number of autoimmune disorders such as rheumatoid arthritis, lupus, and psoriasis as well as diabetes, hepatitis, and sclerosis among a number of others.{34485,34486,34487,34488,34489,34490,34491} Cayman’s HLA-DR Monoclonal Antibody (Clone L243) detects HLA-DR with or without attached ligand. The predicated size of the HLA-DRα or HLA-DRβ subunits is ~29-30 kDa.

宿主来源:

Mouse

实验应用:

FC, ICC, IF, IHC, IP, and WB

同种型:

IgG2a

免疫原:

Human lymphoblastoid cell line (RPMI 8866)

克隆号:

L243

保存温度:

-20