PAMAM Dendrimer G4.5 Carboxylate (sodium salt) (water solution)-其他-ELISA_抗体_蛋白_核苷酸

首页产品中心其他

PAMAM Dendrimer G4.5 Carboxylate (sodium salt) (water solution)

品牌：Cayman

官网链接

说明书

折扣/货期

货号：39109-1 g	规格：1 g	目录价：￥8484
货号：39109	规格：500 mg	目录价：￥4466

产品详情

产品名称:

PAMAM Dendrimer G4.5 Carboxylate (sodium salt) (water solution)

别名:

PAMAM G4.5 Carboxylate|Polyamidoamine Dendrimer G4.5 Carboxylate

产品描述:

PAMAM dendrimer G4.5 carboxylate (PAMAM G4.5 carboxylate) is a polyamidoamine (PAMAM) dendrimer with carboxylate termini that has been used as a drug delivery system.{67597} It is approximately 87.9 Å in diameter in water and has 96 surface groups.{67554} Unlike the amine-terminated PAMAM G5.0 (Item No. 39075), it does not rupture bilayer lipid membranes when used at a concentration of 50 µM.{67598} PAMAM G4.5 carboxylate disulfur-linked aggregates (10 µg/ml) encapsulating the phenol ferulic acid (Item No. 19871) and the mitotic inhibitor paclitaxel (Item No. 10461) induce apoptosis and decrease the mitochondrial membrane potential in multidrug-resistant KB-8-5 epidermal carcinoma cells.{67597} Complexes of PAMAM G4.5 carboxylate with the active component of cisplatin are cytotoxic to A2780 ovarian cancer cells (IC50 = 620 nM).{67596} A fluorescently labeled form of PAMAM G4.5 carboxylate selectively accumulates in tumors and kidneys over liver, spleen, heart, and lungs in a 4T1 murine mammary carcinoma model.{67599}

保存温度:

-20

运输温度:

-20

预期分子量:

26251.9

产品形式:

A solution in water

有效期:

730

CAS号:

202009-66-3