Prostatic Acid Phosphatase (mouse, recombinant) - 深圳欣博盛生物科技有限公司

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Prostatic Acid Phosphatase (mouse, recombinant)

品牌： Cayman

产品货号： 38071

规格： 100 µg

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折后价：

数量： - +

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产品名称:

Prostatic Acid Phosphatase (mouse, recombinant)
别名:

Acid Phosphatase 3|PAcP|PAP|PPAP|Protein Tyrosine Phosphatase ACP3|Secretory Prostatic Acid Phosphatase
产品描述:

Prostatic acid phosphatase is a member of the protein tyrosine phosphatase (PTP) family.{64874} It exists as a homodimer and each monomer is composed of a signal peptide, which, once cleaved, produces a catalytically active enzyme, and two domains where the larger domain contains an α/β-hydrolase fold and the smaller domain contains mostly α-helices. Alternative splicing of the gene encoding prostatic acid phosphatase, Acp3, generates a secreted form that is expressed in prostate tissues and semen, and a transmembrane form that is expressed in several tissues.{64875,14279,64876} In addition to its phosphatase activity, prostatic acid phosphatase also has ectonucleotidase activity against AMP, ADP, and ATP in a pH-dependent manner.{64877} Intrathecal administration of recombinant mouse prostatic acid phosphatase has antinociceptive activity in a mouse model of inflammatory pain induced by complete Freund’s adjuvant (CFA). Serum levels of prostatic acid phosphatase are increased in patients with prostate cancer and vaginal prostatic acid phosphatase activity has been used as a marker of sexual abuse.{64874,64878} Cayman’s Prostatic Acid Phosphatase (mouse, recombinant) protein consists of 361 amino acids, has a calculated molecular weight of 42 kDa, and a predicted N-terminus of Lys32 after signal peptide cleavage. By SDS-PAGE, under reducing conditions, the apparent molecular mass of the protein is 47 kDa due to glycosylation.
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-80
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-80
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Lyophilized from sterile PBS, pH 7.4
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365
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美国
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≥98% estimated by SDS-PAGE
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