货号:AG-40A-0059-C050 | 规格:50 ug | 目录价:¥5040 |
产品详情
产品名称:
ST2 (human):Fc (human) (rec.)
别名:
Interleukin-1 Receptor-like 1; IL-1 Receptor-like 1; IL1RL1; IL-33 Receptor; Interleukin-33 Receptor
产品描述:
The ST2 (Interleukin-1 receptor-like 1; Interleukin-33 receptor) gene was originally identified as a gene induced by serum or oncogene expression in fibroblasts. The gene produces a shorter soluble secreted form (ST2) and a longer, transmembrane form (ST2L) by alternative splicing. Soluble ST2 has been shown to downregulate the expression of TLR1 and TLR4. ST2L negatively regulates TLR4 signaling and induces endotoxin tolerance, and enhances Th2 responses. IL-33 is the specific ligand for ST2L.
宿主来源:
HEK 293 cells
靶标/特异性:
Binds to human IL-33.
产品浓度:
~0.5mg/ml
保存温度:
-20°C
运输温度:
BLUE ICE
预期分子量:
~90kDa (SDS-PAGE)
产品形式:
liquid
存储溶液:
Liquid. 0.2µm-filtered solution in PBS, pH 7.2.
有效期:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>90% (SDS-PAGE)
生物活性:
Interacts with human IL-33.
内毒素水平:
<0.1EU/µg purified protein (LAL test; Lonza).
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